Avoiding sequential scans with OR join condition

Hello. I have a query like:

SELECT big_table.*
FROM little_table, big_table
WHERE little_table.x = 10 AND
little_table.y IN (big_table.y1, big_table.y2);

I have indexes on both big_table.y1 and big_table.y2 and on
little_table.x and little_table.y. The result is a sequential scan of
big_table. In order to prevent this, I've rewritten the query as:

SELECT big_table.*
FROM little_table, big_table
WHERE little_table.x = 10 AND
little_table.y = big_table.y1
UNION
SELECT big_table.*
FROM little_table, big_table
WHERE little_table.x = 10 AND
little_table.y = big_table.y2

which does allow an index scan, but suffers from two separate queries
along with a unique sort, which, from the data, represents 90% of the
tuples returned by both queries.

Is there any way to write the first query such that indexes will be used?

Mike Mascari