How to speeed up the query performance

How do I speed up the quey performance if I've a query like this :
Does 'not in' command will affected the performance?.

select
ts.transportid,ts.transporttype,ts.transportcapacity,ts.transportstatus,ts.routecoverage,ts.transportregnumber

from transportsetup ts
where ts.bizid = 'B126'
and ts.deletestatus = 0
and ts.transportid not in ( select t.transportid
f rom transportsetup
t,servicedetail s,logisticservice l
where t.bizid=l.bizid
and
l.serviceid=s.serviceid
and
t.transportid=s.transportid
and t.bizid = 'B126'
and l.status='Pending'
or t.bizid=l.bizid
and
l.serviceid=s.serviceid
and
t.transportid=s.transportid
and t.bizid =
'B126' and l.status='Reserved' )
order by ts.transporttype;

Any help pretty much appreciated. Thanks